Immune dysregulation in primary immune thrombocytopenia patients
نویسندگان
چکیده
منابع مشابه
Human platelet antigens polymorphisms: Association to primary immune thrombocytopenia in the Iranian patients
Background: Human platelet antigens (HPAs) are part of platelet GP complexes have the potential to contribute to the autoantibody production. Moreover, these antigens demonstrate different patterns of distribution on different ethnic groups and variation in some types of diseases. This study was objected to determine the incidence of HPA-1 to -5 and -15 polymorphisms in the Iranians suffering f...
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Sunitinib is an oral tyrosine kinase inhibitor which prevents tumor growth and metastatic progression. It was approved for treatment of advanced renal cell cancer, gastrointestinal stromal tumor and advanced pancreatic neuroendocrine tumors. It has several adverse reactions on multi organ systems including hematologic system. Although the neutropenia and thrombocytopenia commonly happens as Gra...
متن کاملSunitinib Induced Immune Thrombocytopenia
Sunitinib is an oral tyrosine kinase inhibitor which prevents tumor growth and metastatic progression. It was approved for treatment of advanced renal cell cancer, gastrointestinal stromal tumor and advanced pancreatic neuroendocrine tumors. It has several adverse reactions on multi organ systems including hematologic system. Although the neutropenia and thrombocytopenia commonly happens as Gra...
متن کاملFatigue in adult patients with primary immune thrombocytopenia.
BACKGROUND Patients with primary immune thrombocytopenia (ITP) commonly describe symptoms of fatigue. However, hematologists rarely consider fatigue a manifestation of ITP. OBJECTIVES To document the prevalence of fatigue among patients with ITP and to determine the patient characteristics that are associated with fatigue. Using a cross-sectional design, we surveyed 1871 members of the U...
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Hodgkin lymphoma (HL) as a malignant tumor presents with lymphadenopathy and systemic complaints. The origin of this tumor is mostly suggested to be B lymphocytes. There is a close relationship between autoimmunity and HL, but the mechanism of this immune syndromes is unclear. Immune thrombocytopenia (ITP) is the most common autoimmune syndrome which may present before, at the same time, and ev...
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ژورنال
عنوان ژورنال: Hematology
سال: 2018
ISSN: 1607-8454
DOI: 10.1080/10245332.2018.1435021